Multiple Kernel Panics running Mac OS X El Capitan 10.11.4 Beta (build 15E56a)

Model: iMac Retina 5K 27-inch Late 2015
CPU: 4 GHz Intel Core i7
RAM: 48GB 1867 MHz DDR3
GPU: AMD Radeon R9 M395X 4GB

Diagnostic Report:
Anonymous UUID: FE291945-9E12-D0D2-25EE-893F6535D011

Sun Mar 6 15:23:20 2016

*** Panic Report ***
panic(cpu 2 caller 0xffffff8003fce40a): Kernel trap at 0xffffff8003f20225, type 14=page fault, registers:
CR0: 0x0000000080010033, CR2: 0x0000000000000000, CR3: 0x0000000a496000e6, CR4: 0x00000000003627e0
RAX: 0x0000000000000030, RBX: 0x0000000000000000, RCX: 0x0000000000000002, RDX: 0xffffff80613be218
RSP: 0xffffff856ec3b920, RBP: 0xffffff856ec3b950, RSI: 0xffffff856ec3b9cc, RDI: 0xffffff80613be1c0
R8: 0x0000000000000000, R9: 0x0000000000000000, R10: 0x0000000000000010, R11: 0x000000010dc90000
R12: 0xffffff856ec3b9cc, R13: 0xffffff80613be1c0, R14: 0xffffff806eec9000, R15: 0xffffff80613be1c0
RFL: 0x0000000000010287, RIP: 0xffffff8003f20225, CS: 0x0000000000000008, SS: 0x0000000000000010
Fault CR2: 0x0000000000000000, Error code: 0x0000000000000000, Fault CPU: 0x2, PL: 1

Backtrace (CPU 2), Frame : Return Address
0xffffff856ec3b5b0 : 0xffffff8003edab12
0xffffff856ec3b630 : 0xffffff8003fce40a
0xffffff856ec3b810 : 0xffffff8003fec273
0xffffff856ec3b830 : 0xffffff8003f20225
0xffffff856ec3b950 : 0xffffff8003f1f282
0xffffff856ec3ba80 : 0xffffff800447dd4b
0xffffff856ec3baa0 : 0xffffff7f863246c6
0xffffff856ec3baf0 : 0xffffff7f8631ff07
0xffffff856ec3bb40 : 0xffffff7f86325354
0xffffff856ec3bba0 : 0xffffff7f86326328
0xffffff856ec3bbe0 : 0xffffff80044df277
0xffffff856ec3bd20 : 0xffffff8003f97cc0
0xffffff856ec3be30 : 0xffffff8003edf283
0xffffff856ec3be60 : 0xffffff8003ec28b8
0xffffff856ec3bea0 : 0xffffff8003ed2665
0xffffff856ec3bf10 : 0xffffff8003fb8bda
0xffffff856ec3bfb0 : 0xffffff8003feca96
Kernel Extensions in backtrace:
com.apple.iokit.IOAcceleratorFamily2(205.3)[1B6944F0-F0F4-3D26-892C-46EB6C5C7433]@0xffffff7f86310000->0xffffff7f8637bfff
dependency: com.apple.iokit.IOPCIFamily(2.9)[0EB3F24F-395B-3F08-B904-D5E0B6A31A2A]@0xffffff7f8472c000
dependency: com.apple.iokit.IOGraphicsFamily(2.4.1)[172C2960-EDF5-382D-80A5-C13E97D74880]@0xffffff7f85365000

BSD process name corresponding to current thread: com.apple.WebKit
Boot args: -v

Mac OS version:
15E56a

Kernel version:
Darwin Kernel Version 15.4.0: Fri Feb 26 21:17:08 PST 2016; root:xnu-3248.40.184~2/RELEASE_X86_64
Kernel UUID: 0624E9B5-75BB-396D-8D54-173FE3854101
Kernel slide: 0x0000000003c00000
Kernel text base: 0xffffff8003e00000
__HIB text base: 0xffffff8003d00000
System model name: iMac17,1 (Mac-B809C3757DA9BB8D)

System uptime in nanoseconds: 315716014926438
last loaded kext at 54570605408: com.apple.iokit.SCSITaskUserClient 3.7.7 (addr 0xffffff7f85209000, size 45056)
loaded kexts:
com.nvidia.CUDA 1.1.0
zoom.us.ZoomAudioDevice 1.1
com.Cycling74.driver.Soundflower 1.6.7
at.obdev.nke.LittleSnitch 4362
com.Areca.ArcMSR 1.3.7
com.apple.iokit.SCSITaskUserClient 3.7.7
com.apple.driver.AppleTopCaseHIDEventDriver 86
com.apple.driver.AppleHSBluetoothDriver 86
com.apple.driver.AGPM 110.21.18
com.apple.driver.ApplePlatformEnabler 2.6.0d0
com.apple.driver.X86PlatformShim 1.0.0
com.apple.filesystems.autofs 3.0
com.apple.driver.AppleMikeyHIDDriver 124
com.apple.iokit.IOBluetoothSerialManager 4.4.4f4
com.apple.driver.AppleOSXWatchdog 1
com.apple.driver.AppleMikeyDriver 274.7
com.apple.driver.AppleHDAHardwareConfigDriver 274.7
com.apple.driver.AppleHDA 274.7
com.apple.driver.AudioAUUC 1.70
com.apple.driver.AppleGraphicsDevicePolicy 3.7.7
com.apple.driver.AppleUpstreamUserClient 3.6.1
com.apple.kext.AMDFramebuffer 1.4.2
com.apple.driver.pmtelemetry 1
com.apple.iokit.IOUserEthernet 1.0.1
com.apple.driver.AppleIntelSKLGraphics 10.1.2
com.apple.AMDRadeonX4000 1.4.2
com.apple.Dont_Steal_Mac_OS_X 7.0.0
com.apple.driver.ACPI_SMC_PlatformPlugin 1.0.0
com.apple.driver.AppleMuxControl 3.12.6
com.apple.driver.AppleBacklight 170.8.9
com.apple.driver.AppleHV 1
com.apple.driver.AppleIntelPCHPMC 1.1
com.apple.driver.AppleSMCLMU 208
com.apple.kext.AMD9000Controller 1.4.2
com.apple.driver.AppleMCCSControl 1.2.13
com.apple.driver.AppleIntelSKLGraphicsFramebuffer 10.1.2
com.apple.iokit.BroadcomBluetoothHostControllerUSBTransport 4.4.4f4
com.apple.driver.AppleIntelSlowAdaptiveClocking 4.0.0
com.apple.driver.AppleFIVRDriver 4.1.0
com.apple.driver.AppleThunderboltIP 3.0.8
com.apple.driver.AppleFileSystemDriver 3.0.1
com.apple.driver.CoreStorageFsck 517.20.1
com.apple.AppleFSCompression.AppleFSCompressionTypeDataless 1.0.0d1
com.apple.AppleFSCompression.AppleFSCompressionTypeZlib 1.0.0
com.apple.BootCache 38
com.apple.iokit.IOBluetoothUSBDFU 4.4.4f4
com.apple.iokit.IOAHCIBlockStorage 2.8.5
com.apple.driver.AppleSDXC 1.7.0
com.apple.iokit.AppleBCM5701Ethernet 10.2.0
com.apple.driver.AirPort.Brcm4360 1040.1.1a4
com.apple.driver.AppleAHCIPort 3.1.8
com.apple.driver.AppleRTC 2.0
com.apple.driver.AppleACPIButtons 4.0
com.apple.driver.AppleHPET 1.8
com.apple.driver.AppleSMBIOS 2.1
com.apple.driver.AppleACPIEC 4.0
com.apple.driver.AppleAPIC 1.7
com.apple.nke.applicationfirewall 163
com.apple.security.quarantine 3
com.apple.security.TMSafetyNet 8
com.apple.iokit.IOSCSIBlockCommandsDevice 3.7.7
com.apple.driver.AppleHIDKeyboard 181
com.apple.driver.AppleMultitouchDriver 304.10.2
com.apple.driver.AppleHIDTransport 5
com.apple.driver.IOBluetoothHIDDriver 4.4.4f4
com.apple.kext.triggers 1.0
com.apple.iokit.IOSerialFamily 11
com.apple.driver.DspFuncLib 274.7
com.apple.kext.OSvKernDSPLib 525
com.apple.iokit.IOSurface 108.2.1
com.apple.driver.IOPlatformPluginLegacy 1.0.0
com.apple.driver.AppleGraphicsControl 3.12.6
com.apple.driver.AppleBacklightExpert 1.1.0
com.apple.iokit.IONDRVSupport 2.4.1
com.apple.driver.CoreCaptureResponder 1
com.apple.driver.X86PlatformPlugin 1.0.0
com.apple.driver.AppleHDAController 274.7
com.apple.iokit.IOHDAFamily 274.7
com.apple.iokit.IOAudioFamily 204.3
com.apple.vecLib.kext 1.2.0
com.apple.driver.IOPlatformPluginFamily 6.0.0d7
com.apple.driver.AppleSMBusPCI 1.0.14d1
com.apple.kext.AMDSupport 1.4.2
com.apple.driver.AppleSMC 3.1.9
com.apple.driver.AppleSMBusController 1.0.14d1
com.apple.AppleGraphicsDeviceControl 3.12.6
com.apple.iokit.IOAcceleratorFamily2 205.3
com.apple.iokit.IOGraphicsFamily 2.4.1
com.apple.iokit.IOBluetoothHostControllerUSBTransport 4.4.4f4
com.apple.iokit.IOBluetoothFamily 4.4.4f4
com.apple.iokit.IOSlowAdaptiveClockingFamily 1.0.0
com.apple.driver.AppleThunderboltEDMSink 4.1.1
com.apple.driver.AppleThunderboltDPInAdapter 4.1.3
com.apple.driver.AppleThunderboltDPOutAdapter 4.1.3
com.apple.driver.AppleThunderboltDPAdapterFamily 4.1.3
com.apple.driver.AppleThunderboltPCIUpAdapter 2.0.2
com.apple.driver.AppleThunderboltPCIDownAdapter 2.0.2
com.apple.driver.CoreStorage 517.20.1
com.apple.driver.usb.IOUSBHostHIDDevice 1.0.1
com.apple.driver.usb.cdc 5.0.0
com.apple.driver.usb.networking 5.0.0
com.apple.driver.usb.AppleUSBHostCompositeDevice 1.0.1
com.apple.driver.AppleXsanScheme 3
com.apple.iokit.IOSCSIParallelFamily 3.0.0
com.apple.iokit.IOSCSIArchitectureModelFamily 3.7.7
com.apple.driver.AppleThunderboltNHI 4.0.4
com.apple.iokit.IOThunderboltFamily 6.0.2
com.apple.iokit.IOEthernetAVBController 1.0.3b3
com.apple.iokit.IO80211Family 1110.26
com.apple.driver.mDNSOffloadUserClient 1.0.1b8
com.apple.iokit.IONetworkingFamily 3.2
com.apple.driver.corecapture 1.0.4
com.apple.driver.AppleUSBMergeNub 900.4.1
com.apple.iokit.IOAHCIFamily 2.8.1
com.apple.driver.usb.AppleUSBXHCIPCI 1.0.1
com.apple.driver.usb.AppleUSBXHCI 1.0.1
com.apple.iokit.IOUSBFamily 900.4.1
com.apple.iokit.IOUSBHostFamily 1.0.1
com.apple.driver.AppleUSBHostMergeProperties 1.0.1
com.apple.driver.AppleEFINVRAM 2.0
com.apple.driver.AppleEFIRuntime 2.0
com.apple.iokit.IOHIDFamily 2.0.0
com.apple.iokit.IOSMBusFamily 1.1
com.apple.security.sandbox 300.0
com.apple.kext.AppleMatch 1.0.0d1
com.apple.driver.AppleKeyStore 2
com.apple.driver.AppleMobileFileIntegrity 1.0.5
com.apple.driver.AppleCredentialManager 1.0
com.apple.driver.DiskImages 417.2
com.apple.iokit.IOStorageFamily 2.1
com.apple.iokit.IOReportFamily 31
com.apple.driver.AppleFDEKeyStore 28.30
com.apple.driver.AppleACPIPlatform 4.0
com.apple.iokit.IOPCIFamily 2.9
com.apple.iokit.IOACPIFamily 1.4
com.apple.kec.pthread 1
com.apple.kec.corecrypto 1.0
com.apple.kec.Libm 1

System Profile:
Graphics: AMD Radeon R9 M395X, AMD Radeon R9 M395X, PCIe, 4096 MB
AirPort: spairport_wireless_card_type_airport_extreme (0x14E4, 0x14A), Broadcom BCM43xx 1.0 (7.21.95.172.1a4)
Bluetooth: Version 4.4.4f4 17685, 3 services, 27 devices, 1 incoming serial ports
PCI Card: pci17d3,1880, RAID Controller, Thunderbolt@10,0,0
PCI Card: pci1b4b,9182, AHCI Controller, Thunderbolt@194,0,0
Thunderbolt Bus: iMac, Apple Inc., 28.1
Thunderbolt Device: ARC8050-T2, Areca, 1, 22.1
Thunderbolt Device: eSata Hub, LaCie, 3, 26.1
Memory Module: BANK 0/DIMM0, 16 GB, DDR3, 1867 MHz, 0x85F7, 0x48363432475534324733313836470000
Memory Module: BANK 0/DIMM1, 16 GB, DDR3, 1867 MHz, 0x85F7, 0x48363432475534324733313836470000
Memory Module: BANK 1/DIMM0, 8 GB, DDR3, 1867 MHz, 0x510, 0x475238475331364B353132382D31382000
Memory Module: BANK 1/DIMM1, 8 GB, DDR3, 1867 MHz, 0x510, 0x475238475331364B353132382D31382000
USB Device: USB 3.0 Bus
USB Device: Bluetooth USB Host Controller
USB Device: FaceTime HD Camera (Built-in)
USB Device: USB Swipe Reader
USB Device: DYMO LabelWriter 450
Serial ATA Device: APPLE SSD SM1024G, 1 TB
Serial ATA Device: spsata_pm_name
Serial ATA Device: spsata_pm_name
Network Service: Ethernet, Ethernet, en0
Network Service: Wi-Fi, AirPort, en1
Model: iMac17,1, BootROM IM171.0105.B07, 4 processors, Intel Core i7, 4 GHz, 48 GB, SMC 2.34f2

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Doing a couple of Google searches, it would appear that your AMD Radeon r9 m395x GPU is overheating your computer and that that is causing the kernel panics. Easily tested with temporarily turning GPU computing off (BOINC Manager->(View->Advanced view->)Activity->Suspend GPU).

If that fixes things, you'll have to check into options to make sure that your OS X turns the fans on when it's needed, or waiting until Apple comes with a solution to this problem, not use the GPU for calculations.

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