I'm a Chinese. I was running boinc last night in a 5-year-old laptop. when I wake up, win10 reports windows detected a hard disk problem. Maybe boinc cause the problem.
I then use DiskGenius to diagnose my disk. The details are:
LBA: 139559595 Cylinder: 8687 Head: 46 Sector: 43 Total sector number: 3 Time: 10046 Error message: IO Device Timeout.
I click fix error in DiskGenius, then a message pop up:
写扇区错误！ 磁盘: HD0:HitachiHTS543232A7A384(298GB) 起始于 139556655 扇区 共 3 个扇区。
Which I translate: Error writing to sector! Disk: D0HD0:HitachiHTS543232A7A384(298GB) Starts from 139556655 sector, totally 3 sectors.
I wanna find out which files were affected. After some google search, I can use nfi.exe to do the job.

nfi.exe \Device\Harddisk0\DR0 139559595
nfi.exe \Device\Harddisk0\DR0 139556655

PS: I'm running poem@home, rosetta@home and universe@home. But there is no folder named "C:\Program Files\BOINC\projects" at present.

Here's the detail output, what do you guys think?

C:\Windows\system32>D:\微软\我\桌面\nfi.exe \Device\Harddisk0\DR0 139559595
NTFS File Sector Information Utility.
Copyright (C) Microsoft Corporation 1999. All rights reserved.


***Physical sector 139559595 (0x85182ab) is in file number 278420 on drive C.
\Users\
    $STANDARD_INFORMATION (resident)
    $FILE_NAME (resident)
    $FILE_NAME (resident)
    $DATA (nonresident)
        physical sectors 139559423-139559926 (0x85181ff-0x85183f6)

C:\Windows\system32>D:\微软\我\桌面\nfi.exe \Device\Harddisk0\dr0 139556655
NTFS File Sector Information Utility.
Copyright (C) Microsoft Corporation 1999. All rights reserved.


***Physical sector 139556655 (0x851772f) is in file number 210069 on drive C.
[b]\PROGRA~3\BOINC\projects\BOINCB~1.ORG\MINIRO~1.ZIP[/b]
    $DATA (nonresident)
        physical sectors 39707527-39707686 (0x25de387-0x25de426)
        physical sectors 22501967-22502094 (0x1575a4f-0x1575ace)
        physical sectors 54288847-54289198 (0x33c61cf-0x33c632e)
        physical sectors 110273071-110273358 (0x692a22f-0x692a34e)
        physical sectors 110273487-110273678 (0x692a3cf-0x692a48e)
        physical sectors 112216231-112216838 (0x6b048a7-0x6b04b06)
        physical sectors 90320151-90320758 (0x5622d17-0x5622f76)
        physical sectors 81118695-81118918 (0x4d5c5e7-0x4d5c6c6)
        physical sectors 108953815-108954102 (0x67e80d7-0x67e81f6)
        physical sectors 39707399-39707526 (0x25de307-0x25de386)
        physical sectors 108953623-108953814 (0x67e8017-0x67e80d6)
        physical sectors 115047527-115047726 (0x6db7c67-0x6db7d2e)
        physical sectors 81112423-81112822 (0x4d5ad67-0x4d5aef6)
        physical sectors 87328215-87328606 (0x53485d7-0x534875e)
        physical sectors 109552511-109552734 (0x687a37f-0x687a45e)
        physical sectors 123943471-123943950 (0x7633a2f-0x7633c0e)
        physical sectors 19434471-19434758 (0x1288be7-0x1288d06)
        physical sectors 19434887-19435086 (0x1288d87-0x1288e4e)
        physical sectors 33195087-33195270 (0x1fa844f-0x1fa8506)
        physical sectors 42775023-42775198 (0x28cb1ef-0x28cb29e)
        physical sectors 68785015-68785630 (0x4199377-0x41995de)
        physical sectors 85459959-85460574 (0x51803f7-0x518065e)
        physical sectors 109987735-109987862 (0x68e4797-0x68e4816)
        physical sectors 123943343-123943470 (0x76339af-0x7633a2e)
        physical sectors 108106455-108107070 (0x67192d7-0x671953e)
        physical sectors 111106079-111106358 (0x69f581f-0x69f5936)
        physical sectors 114947743-114948358 (0x6d9f69f-0x6d9f906)
        physical sectors 110018759-110018934 (0x68ec0c7-0x68ec176)
        physical sectors 66240927-66241198 (0x3f2c19f-0x3f2c2ae)
        physical sectors 128702599-128702814 (0x7abd887-0x7abd95e)
        physical sectors 17416895-17417518 (0x109c2bf-0x109c52e)
        physical sectors 111106359-111106694 (0x69f5937-0x69f5a86)
        physical sectors 113014807-113015238 (0x6bc7817-0x6bc79c6)
        physical sectors 107639111-107639726 (0x66a7147-0x66a73ae)
        physical sectors 33194911-33195086 (0x1fa839f-0x1fa844e)
        physical sectors 35080167-35080414 (0x21747e7-0x21748de)
        physical sectors 35502807-35503062 (0x21dbad7-0x21dbbd6)
        physical sectors 36645255-36645510 (0x22f2987-0x22f2a86)
        physical sectors 39705791-39705918 (0x25ddcbf-0x25ddd3e)
        physical sectors 42661639-42661934 (0x28af707-0x28af82e)
        physical sectors 68591031-68591398 (0x4169db7-0x4169f26)
        physical sectors 88581439-88581670 (0x547a53f-0x547a626)
        physical sectors 88581799-88581934 (0x547a6a7-0x547a72e)
        physical sectors 108979599-108979846 (0x67ee58f-0x67ee686)
        physical sectors 109687055-109687182 (0x689b10f-0x689b18e)
        physical sectors 109957367-109957494 (0x68dd0f7-0x68dd176)
        physical sectors 109957631-109957758 (0x68dd1ff-0x68dd27e)
        physical sectors 110920951-110921574 (0x69c84f7-0x69c8766)
        physical sectors 111448007-111448630 (0x6a48fc7-0x6a49236)
        physical sectors 111789407-111789822 (0x6a9c55f-0x6a9c6fe)
        physical sectors 111934183-111934806 (0x6abfae7-0x6abfd56)
        physical sectors 42661487-42661630 (0x28af66f-0x28af6fe)
        physical sectors 112593855-112593982 (0x6b60bbf-0x6b60c3e)
        physical sectors 66241199-66241326 (0x3f2c2af-0x3f2c32e)
        physical sectors 109957495-109957622 (0x68dd177-0x68dd1f6)
        physical sectors 35503063-35503230 (0x21dbbd7-0x21dbc7e)
        physical sectors 109957759-109957990 (0x68dd27f-0x68dd366)
        physical sectors 109687183-109687422 (0x689b18f-0x689b27e)
        physical sectors 110273359-110273486 (0x692a34f-0x692a3ce)
        physical sectors 108979471-108979598 (0x67ee50f-0x67ee58e)
        physical sectors 88581671-88581798 (0x547a627-0x547a6a6)
        physical sectors 88581311-88581438 (0x547a4bf-0x547a53e)
        physical sectors 68590775-68590902 (0x4169cb7-0x4169d36)
        physical sectors 39705919-39706110 (0x25ddd3f-0x25dddfe)
        physical sectors 111789823-111790030 (0x6a9c6ff-0x6a9c7ce)
        physical sectors 128702815-128703086 (0x7abd95f-0x7abda6e)
        physical sectors 112593359-112593854 (0x6b609cf-0x6b60bbe)
        physical sectors 114012239-114012478 (0x6cbb04f-0x6cbb13e)
        physical sectors 109686927-109687054 (0x689b08f-0x689b10e)
        physical sectors 114012671-114012862 (0x6cbb1ff-0x6cbb2be)
        physical sectors 123400831-123401150 (0x75af27f-0x75af3be)
        physical sectors 128702471-128702598 (0x7abd807-0x7abd886)
        physical sectors 35502607-35502806 (0x21dba0f-0x21dbad6)
        physical sectors 34922927-34923366 (0x214e1af-0x214e366)
        physical sectors 27618079-27618398 (0x1a56b1f-0x1a56c5e)
        physical sectors 35641143-35641334 (0x21fd737-0x21fd7f6)
        physical sectors 40765639-40766022 (0x26e08c7-0x26e0a46)
        physical sectors 53723303-53723934 (0x333c0a7-0x333c31e)
        physical sectors 67683303-67683566 (0x408c3e7-0x408c4ee)
        physical sectors 67683695-67683934 (0x408c56f-0x408c65e)
        physical sectors 69862623-69862766 (0x42a04df-0x42a056e)
        physical sectors 71620327-71620982 (0x444d6e7-0x444d976)
        physical sectors 108979847-108980086 (0x67ee687-0x67ee776)
        physical sectors 109686799-109686926 (0x689b00f-0x689b08e)
        physical sectors 139556455-139556838 (0x8517667-0x85177e6)
        physical sectors 71657071-71657702 (0x445666f-0x44568e6)
        physical sectors 35080415-35080790 (0x21748df-0x2174a56)
        physical sectors 73374991-73375478 (0x45f9d0f-0x45f9ef6)
        physical sectors 77422407-77423038 (0x49d5f47-0x49d61be)
        physical sectors 34923367-34923558 (0x214e367-0x214e426)
        physical sectors 35641463-35641774 (0x21fd877-0x21fd9ae)
        physical sectors 85890167-85890798 (0x51e9477-0x51e96ee)
        physical sectors 40766023-40766270 (0x26e0a47-0x26e0b3e)
        physical sectors 86327255-86327886 (0x5253fd7-0x525424e)
        physical sectors 79536407-79536654 (0x4bda117-0x4bda20e)
        physical sectors 86348039-86348366 (0x5259107-0x525924e)
        physical sectors 108903911-108904542 (0x67dbde7-0x67dc05e)
        physical sectors 69862767-69863022 (0x42a056f-0x42a066e)
        physical sectors 110444783-110445094 (0x69540ef-0x6954226)
        physical sectors 110697735-110698366 (0x6991d07-0x6991f7e)
        physical sectors 139556839-139557078 (0x85177e7-0x85178d6)
        physical sectors 123401151-123401454 (0x75af3bf-0x75af4ee)
        physical sectors 107790031-107790238 (0x66cbecf-0x66cbf9e)
        physical sectors 79536023-79536406 (0x4bd9f97-0x4bda116)
        physical sectors 70279151-70279782 (0x4305fef-0x4306266)
        physical sectors 67683567-67683694 (0x408c4ef-0x408c56e)
        physical sectors 86347735-86347862 (0x5258fd7-0x5259056)
        physical sectors 110444591-110444782 (0x695402f-0x69540ee)
        physical sectors 108850207-108850630 (0x67cec1f-0x67cedc6)
        physical sectors 112373207-112373838 (0x6b2add7-0x6b2b04e)
        physical sectors 114302671-114302830 (0x6d01ecf-0x6d01f6e)
        physical sectors 68590903-68591030 (0x4169d37-0x4169db6)
        physical sectors 114303079-114303302 (0x6d02067-0x6d02146)
        physical sectors 114989447-114990102 (0x6da9987-0x6da9c16)
        physical sectors 115185575-115186206 (0x6dd97a7-0x6dd9a1e)
        physical sectors 139552639-139553270 (0x851677f-0x85169f6)
        physical sectors 114012479-114012670 (0x6cbb13f-0x6cbb1fe)
        physical sectors 55053215-55053574 (0x3480b9f-0x3480d06)
        physical sectors 17545327-17545790 (0x10bb86f-0x10bba3e)
        physical sectors 35819055-35819694 (0x2228e2f-0x22290ae)
        physical sectors 36256703-36257342 (0x2293bbf-0x2293e3e)
        physical sectors 54050959-54051598 (0x338c08f-0x338c30e)
        physical sectors 70469207-70469846 (0x4334657-0x43348d6)
        physical sectors 109120095-109120734 (0x6810a5f-0x6810cde)
        physical sectors 110979151-110979790 (0x69d684f-0x69d6ace)
        physical sectors 111068567-111069206 (0x69ec597-0x69ec816)
        physical sectors 112802367-112803006 (0x6b93a3f-0x6b93cbe)
        physical sectors 115006735-115007374 (0x6dadd0f-0x6dadf8e)
        physical sectors 139065823-139066462 (0x849f9df-0x849fc5e)
        physical sectors 36538903-36539550 (0x22d8a17-0x22d8c9e)
        physical sectors 40530351-40530998 (0x26a71af-0x26a7436)
        physical sectors 53288399-53288550 (0x32d1dcf-0x32d1e66)
        physical sectors 73374847-73374990 (0x45f9c7f-0x45f9d0e)
        physical sectors 85070727-85071374 (0x5121387-0x512160e)
        physical sectors 85095903-85096390 (0x51275df-0x51277c6)
        physical sectors 86347863-86348038 (0x5259057-0x5259106)
        physical sectors 110993887-110994534 (0x69da1df-0x69da466)
        physical sectors 123842511-123842710 (0x761afcf-0x761b096)
        physical sectors 123842887-123843158 (0x761b147-0x761b256)
        physical sectors 70832151-70832806 (0x438d017-0x438d2a6)
        physical sectors 73608375-73609030 (0x4632cb7-0x4632f46)
        physical sectors 111201551-111202206 (0x6a0cd0f-0x6a0cf9e)
        physical sectors 111836663-111837318 (0x6aa7df7-0x6aa8086)
        physical sectors 123889063-123889718 (0x76265a7-0x7626836)
        physical sectors 128897183-128897838 (0x7aed09f-0x7aed32e)
        physical sectors 85096391-85096550 (0x51277c7-0x5127866)
        physical sectors 110431599-110432262 (0x6950d6f-0x6951006)
        physical sectors 111933295-111933958 (0x6abf76f-0x6abfa06)
        physical sectors 112390583-112391262 (0x6b2f1b7-0x6b2f45e)
        physical sectors 123562919-123563598 (0x75d6ba7-0x75d6e4e)
        physical sectors 54285903-54286622 (0x33c564f-0x33c591e)
        physical sectors 107949967-107950758 (0x66f2f8f-0x66f32a6)
        physical sectors 108660791-108661582 (0x67a0837-0x67a0b4e)
        physical sectors 111422103-111422894 (0x6a42a97-0x6a42dae)
        physical sectors 26237911-26238710 (0x1905bd7-0x1905ef6)
        physical sectors 46867127-46867926 (0x2cb22b7-0x2cb25d6)
        physical sectors 67462959-67463630 (0x405672f-0x40569ce)
        physical sectors 90421527-90422326 (0x563b917-0x563bc36)
        physical sectors 102275103-102275902 (0x618981f-0x6189b3e)
        physical sectors 110148655-110149278 (0x690bc2f-0x690be9e)
        physical sectors 26769383-26770190 (0x19877e7-0x1987b0e)
        physical sectors 79528583-79529078 (0x4bd8287-0x4bd8476)
        physical sectors 73417335-73418150 (0x4604277-0x46045a6)
        physical sectors 89971431-89972246 (0x55cdae7-0x55cde16)
        physical sectors 113153511-113154326 (0x6be95e7-0x6be9916)
        physical sectors 30987551-30987718 (0x1d8d51f-0x1d8d5c6)
        physical sectors 114892383-114893198 (0x6d91e5f-0x6d9218e)
        physical sectors 115005839-115006654 (0x6dad98f-0x6dadcbe)
        physical sectors 79528407-79528582 (0x4bd81d7-0x4bd8286)
        physical sectors 142800071-142800710 (0x882f4c7-0x882f746)
        physical sectors 34589503-34590326 (0x20fcb3f-0x20fce76)
        physical sectors 42203783-42204606 (0x283fa87-0x283fdbe)
        physical sectors 50939279-50940102 (0x309458f-0x30948c6)
        physical sectors 68760111-68760934 (0x419322f-0x4193566)
        physical sectors 73481743-73482566 (0x4613e0f-0x4614146)
        physical sectors 124293759-124294582 (0x768927f-0x76895b6)
        physical sectors 139025119-139025942 (0x8495adf-0x8495e16)

physical sectors 108850207-108850630 (0x67cec1f-0x67cedc6)
physical sectors 112373207-112373838 (0x6b2add7-0x6b2b04e)
physical sectors 114302671-114302830 (0x6d01ecf-0x6d01f6e)
physical sectors 68590903-68591030 (0x4169d37-0x4169db6)
physical sectors 114303079-114303302 (0x6d02067-0x6d02146)
physical sectors 114989447-114990102 (0x6da9987-0x6da9c16)
physical sectors 115185575-115186206 (0x6dd97a7-0x6dd9a1e)
physical sectors 139552639-139553270 (0x851677f-0x85169f6)
physical sectors 114012479-114012670 (0x6cbb13f-0x6cbb1fe)
physical sectors 55053215-55053574 (0x3480b9f-0x3480d06)
physical sectors 17545327-17545790 (0x10bb86f-0x10bba3e)
physical sectors 35819055-35819694 (0x2228e2f-0x22290ae)
physical sectors 36256703-36257342 (0x2293bbf-0x2293e3e)
physical sectors 54050959-54051598 (0x338c08f-0x338c30e)
physical sectors 70469207-70469846 (0x4334657-0x43348d6)
physical sectors 109120095-109120734 (0x6810a5f-0x6810cde)
physical sectors 110979151-110979790 (0x69d684f-0x69d6ace)
physical sectors 111068567-111069206 (0x69ec597-0x69ec816)
physical sectors 112802367-112803006 (0x6b93a3f-0x6b93cbe)
physical sectors 115006735-115007374 (0x6dadd0f-0x6dadf8e)
physical sectors 139065823-139066462 (0x849f9df-0x849fc5e)
physical sectors 36538903-36539550 (0x22d8a17-0x22d8c9e)
physical sectors 40530351-40530998 (0x26a71af-0x26a7436)
physical sectors 53288399-53288550 (0x32d1dcf-0x32d1e66)
physical sectors 73374847-73374990 (0x45f9c7f-0x45f9d0e)
physical sectors 85070727-85071374 (0x5121387-0x512160e)
physical sectors 85095903-85096390 (0x51275df-0x51277c6)
physical sectors 86347863-86348038 (0x5259057-0x5259106)
physical sectors 110993887-110994534 (0x69da1df-0x69da466)
physical sectors 123842511-123842710 (0x761afcf-0x761b096)
physical sectors 123842887-123843158 (0x761b147-0x761b256)
physical sectors 70832151-70832806 (0x438d017-0x438d2a6)
physical sectors 73608375-73609030 (0x4632cb7-0x4632f46)
physical sectors 111201551-111202206 (0x6a0cd0f-0x6a0cf9e)
physical sectors 111836663-111837318 (0x6aa7df7-0x6aa8086)
physical sectors 123889063-123889718 (0x76265a7-0x7626836)
physical sectors 128897183-128897838 (0x7aed09f-0x7aed32e)
physical sectors 85096391-85096550 (0x51277c7-0x5127866)
physical sectors 110431599-110432262 (0x6950d6f-0x6951006)
physical sectors 111933295-111933958 (0x6abf76f-0x6abfa06)
physical sectors 112390583-112391262 (0x6b2f1b7-0x6b2f45e)
physical sectors 123562919-123563598 (0x75d6ba7-0x75d6e4e)
physical sectors 54285903-54286622 (0x33c564f-0x33c591e)
physical sectors 107949967-107950758 (0x66f2f8f-0x66f32a6)
physical sectors 108660791-108661582 (0x67a0837-0x67a0b4e)
physical sectors 111422103-111422894 (0x6a42a97-0x6a42dae)
physical sectors 26237911-26238710 (0x1905bd7-0x1905ef6)
physical sectors 46867127-46867926 (0x2cb22b7-0x2cb25d6)
physical sectors 67462959-67463630 (0x405672f-0x40569ce)
physical sectors 90421527-90422326 (0x563b917-0x563bc36)
physical sectors 102275103-102275902 (0x618981f-0x6189b3e)
physical sectors 110148655-110149278 (0x690bc2f-0x690be9e)
physical sectors 26769383-26770190 (0x19877e7-0x1987b0e)
physical sectors 79528583-79529078 (0x4bd8287-0x4bd8476)
physical sectors 73417335-73418150 (0x4604277-0x46045a6)
physical sectors 89971431-89972246 (0x55cdae7-0x55cde16)
physical sectors 113153511-113154326 (0x6be95e7-0x6be9916)
physical sectors 30987551-30987718 (0x1d8d51f-0x1d8d5c6)
physical sectors 114892383-114893198 (0x6d91e5f-0x6d9218e)
physical sectors 115005839-115006654 (0x6dad98f-0x6dadcbe)
physical sectors 79528407-79528582 (0x4bd81d7-0x4bd8286)
physical sectors 142800071-142800710 (0x882f4c7-0x882f746)
physical sectors 34589503-34590326 (0x20fcb3f-0x20fce76)
physical sectors 42203783-42204606 (0x283fa87-0x283fdbe)
physical sectors 50939279-50940102 (0x309458f-0x30948c6)
physical sectors 68760111-68760934 (0x419322f-0x4193566)
physical sectors 73481743-73482566 (0x4613e0f-0x4614146)
physical sectors 124293759-124294582 (0x768927f-0x76895b6)
physical sectors 139025119-139025942 (0x8495adf-0x8495e16)[/code][code][/code][code][/code]

You should also post which OS version you are running as well as the version of BOINC. The location of the BOINC data directory can be in one of two places depending on OS version. That is also assuming that you didn't change the location during installation. This folder is typically a hidden folder so you may need to change your settings within Windows to view them.

If you are running Vista or later, look in the C:\ProgramData\BOINC\projects directory.

---

Have you run CHKDSK? That is probably your best hope for recovering any files. You will find any remaining orphaned files in a directory "C:\found.000", but it may be hidden. You can view them with a program such as IsoBuster.

Sorry for the late response.
I'm using Win10 64 bit. BOINC V. 7.6.22
As posted in main thread, the affected file is \PROGRA~3\BOINC\projects\BOINCB~1.ORG\MINIRO~1.ZIP

C:\ProgramData\BOINC\projects\boinc.bakerlab.org_rosetta 的目录
2016/03/25  19:31           181,956 input_rb_03_24_63940_108088__t000__1_C1_robetta.zip
2016/03/14  20:36       197,960,494 minirosetta_database_f513f38.zip

Maybe frequently writing to minirosetta_database_f513f38.zip cause the problem, or maybe my disk is too old. Whatever.

Thank you for your reply.

Thank you. I'll have a try.